Publications
2026
22. Saurav Mallik, Ayala Shiber (2026). The twisted tale of cotranslational protein complex assembly. Current Opinion in Structural Biology DOI: 10.1016/j.sbi.2026.103281.
2025
21. Saurav Mallik, Meir Sylman, Dvir Dahary, Orna Dahan, Shulamit Michaeli, Gerald Spaeth, Yitzhak Pilpel (2025). The evolutionary origin of host association and polycistronic transcription in trypanosomatids. BioRxiv DOI: 10.1101/2025.10.27.684775.
20. Zikun Zhu, Saurav Mallik, Taylor A Stevens, Riming Huang, Emmanuel D Levy, Shu-ou Shan (2025). Principles of cotranslational mitochondrial protein import. Cell DOI: 10.1016/j.cell.2025.07.021.
19. Saurav Mallik, Angel F Cisneros, Christian R Landry, Emmanuel D Levy (2025). Co-translational assembly promotes functional diversification of paralogous proteins. BioRxiv DOI: 10.1101/2025.01.22.634331.
18. Saurav Mallik, Johannes Venezian, Arseniy Lobov, Meta Heidenreich, Hector Garcia-Seisdedos, Todd O Yeates, Ayala Shiber, Emmanuel D Levy (2025). Structural determinants of co-translational protein complex assembly. Cell, 188(3): 764-777.e22.
Highlight in Nature Reviews Molecular Cell Biology
Spotlight in Molecular Cell
2024
17. Angel F Cisneros, Lou Nielly-Thibault, Saurav Mallik, Emmanuel D Levy, Christian R Landry (2024). Mutational biases favor complexity increases in protein interaction networks after gene duplication. Molecular Systems Biology 20:549-572
2022
16. Saurav Mallik, Dan S Tawfik, Emmanuel D Levy (2022). How gene duplication diversifies the landscape of protein oligomeric state and function. Current Opinion in Genetics and Development 76:101966.
2021
15. Mathieu E Rebeaud, Saurav Mallik, Pierre Goloubinoff, Dan S Tawfik (2021). On the evolution of chaperones and cochaperones and the expansion of proteomes across the Tree of Life. Proceedings of the National Academy of Sciences 118(21):e2020885118.
2020
14. Sudipto Basu, Saurav Mallik, Suman Hait, Sudip Kundu (2021). Genome-scale molecular principles of mRNA half-life regulation in yeast. FEBS Journal 288(11):3428-3447.
13. Saurav Mallik, Dan S Tawfik (2020). Determining the interaction status and evolutionary fate of duplicated homomeric proteins. PLoS Computational Biology 16(8): e1008145.
12. Suman Hait, Saurav Mallik, Sudipto Basu, Sudip Kundu (2020). Finding the generalized molecular principles of protein thermal stability. Proteins 88(6):788-808.
2018
11. Saurav Mallik, Sudipto Basu, Suman Hait, Sudip Kundu (2018). Translational regulation of ribosomal protein S15 drives characteristic patterns of protein-mRNA epistasis. Proteins 86(8):827-832.
10. Saurav Mallik, Sudip Kundu (2018). Topology and oligomerization of mono-and oligomeric proteins regulate their half-lives in the cell. Structure 26(6):869-878.e3.
2017
9. Saurav Mallik, Tanaya Ray, Sudip Kundu (2017). Transiently disordered tails accelerate folding of globular proteins. FEBS Letters 591(14):2180-2191.
8. Saurav Mallik, Sudip Kundu (2017). Coevolutionary constraints in the sequence‐space of macromolecular complexes reflect their self-assembly pathways. Proteins 85(7):1183-1189.
7. Saurav Mallik, Sudip Kundu (2017). Modular organization of residue-level contacts shapes the selection pressure on individual amino acid sites of ribosomal proteins. Genome Biology and Evolution 9(4):916-931.
2016
6. Saurav Mallik, Smita Das, Sudip Kundu (2016). Predicting protein folding rate change upon point mutation using residue-level coevolutionary information. Proteins 84(1):3-8.
2015
5. Saurav Mallik, Sudip Kundu (2015). Co-evolutionary constraints of globular proteins correlate with their folding rates. FEBS Letters 589(17):2179-85.
4. Saurav Mallik, Hiroshi Akashi, Sudip Kundu (2015). Assembly constraints drive co-evolution among ribosomal constituents. Nucleic Acids Research 43(11):5352-63.
3. Saurav Mallik, Sudip Kundu (2015). Molecular interactions within the halophilic, thermophilic, and mesophilic prokaryotic ribosomal complexes: clues to environmental adaptation. Journal of Biomolecular Structure and Dynamics 33(3):639-56.
2014
2. Amrita Bhattacherjee, Saurav Mallik, Sudip Kundu (2014). Compensatory mutations occur within the electrostatic interaction range of deleterious mutations in protein structure. Journal of Molecular Evolution 80(1):10-2.
2013
1. Saurav Mallik, Sudip Kundu (2013) A Comparison of Structural and Evolutionary Attributes of Escherichia coli and Thermus thermophilus Small Ribosomal Subunits: Signatures of Thermal Adaptation. PLoS One 8(8):e69898.