Publications
2025
21. Saurav Mallik, Meir Sylman, Dvir Dahary, Orna Dahan, Shulamit Michaeli, Gerald Spaeth, Yitzhak Pilpel (2025). The evolutionary origin of host association and polycistronic transcription in trypanosomatids. BioRxiv DOI: 10.1101/2025.10.27.684775.
20. Zikun Zhu, Saurav Mallik, Taylor A Stevens, Riming Huang, Emmanuel D Levy, Shu-ou Shan (2025). Principles of cotranslational mitochondrial protein import. Cell DOI: 10.1016/j.cell.2025.07.021.
19. Saurav Mallik, Angel F Cisneros, Christian R Landry, Emmanuel D Levy (2025). Co-translational assembly promotes functional diversification of paralogous proteins. BioRxiv DOI: 10.1101/2025.01.22.634331.
18. Saurav Mallik, Johannes Venezian, Arseniy Lobov, Meta Heidenreich, Hector Garcia-Seisdedos, Todd O Yeates, Ayala Shiber, Emmanuel D Levy (2025). Structural determinants of co-translational protein complex assembly. Cell, 188(3): 764-777.e22.
Highlight in Nature Reviews Molecular Cell Biology
Spotlight in Molecular Cell
2024
17. Angel F Cisneros, Lou Nielly-Thibault, Saurav Mallik, Emmanuel D Levy, Christian R Landry (2024). Mutational biases favor complexity increases in protein interaction networks after gene duplication. Molecular Systems Biology 20:549-572
2022
16. Saurav Mallik, Dan S Tawfik, Emmanuel D Levy (2022). How gene duplication diversifies the landscape of protein oligomeric state and function. Current Opinion in Genetics and Development 76:101966.
2021
15. Mathieu E Rebeaud, Saurav Mallik, Pierre Goloubinoff, Dan S Tawfik (2021). On the evolution of chaperones and cochaperones and the expansion of proteomes across the Tree of Life. Proceedings of the National Academy of Sciences 118(21):e2020885118.
2020
14. Sudipto Basu, Saurav Mallik, Suman Hait, Sudip Kundu (2021). Genome-scale molecular principles of mRNA half-life regulation in yeast. FEBS Journal 288(11):3428-3447.
13. Saurav Mallik, Dan S Tawfik (2020). Determining the interaction status and evolutionary fate of duplicated homomeric proteins. PLoS Computational Biology 16(8): e1008145.
12. Suman Hait, Saurav Mallik, Sudipto Basu, Sudip Kundu (2020). Finding the generalized molecular principles of protein thermal stability. Proteins 88(6):788-808.
2018
11. Saurav Mallik, Sudipto Basu, Suman Hait, Sudip Kundu (2018). Translational regulation of ribosomal protein S15 drives characteristic patterns of protein-mRNA epistasis. Proteins 86(8):827-832.
10. Saurav Mallik, Sudip Kundu (2018). Topology and oligomerization of mono-and oligomeric proteins regulate their half-lives in the cell. Structure 26(6):869-878.e3.
2017
9. Saurav Mallik, Tanaya Ray, Sudip Kundu (2017). Transiently disordered tails accelerate folding of globular proteins. FEBS Letters 591(14):2180-2191.
8. Saurav Mallik, Sudip Kundu (2017). Coevolutionary constraints in the sequence‐space of macromolecular complexes reflect their self-assembly pathways. Proteins 85(7):1183-1189.
7. Saurav Mallik, Sudip Kundu (2017). Modular organization of residue-level contacts shapes the selection pressure on individual amino acid sites of ribosomal proteins. Genome Biology and Evolution 9(4):916-931.
2016
6. Saurav Mallik, Smita Das, Sudip Kundu (2016). Predicting protein folding rate change upon point mutation using residue-level coevolutionary information. Proteins 84(1):3-8.
2015
5. Saurav Mallik, Sudip Kundu (2015). Co-evolutionary constraints of globular proteins correlate with their folding rates. FEBS Letters 589(17):2179-85.
4. Saurav Mallik, Hiroshi Akashi, Sudip Kundu (2015). Assembly constraints drive co-evolution among ribosomal constituents. Nucleic Acids Research 43(11):5352-63.
3. Saurav Mallik, Sudip Kundu (2015). Molecular interactions within the halophilic, thermophilic, and mesophilic prokaryotic ribosomal complexes: clues to environmental adaptation. Journal of Biomolecular Structure and Dynamics 33(3):639-56.
2014
2. Amrita Bhattacherjee, Saurav Mallik, Sudip Kundu (2014). Compensatory mutations occur within the electrostatic interaction range of deleterious mutations in protein structure. Journal of Molecular Evolution 80(1):10-2.
2013
1. Saurav Mallik, Sudip Kundu (2013) A Comparison of Structural and Evolutionary Attributes of Escherichia coli and Thermus thermophilus Small Ribosomal Subunits: Signatures of Thermal Adaptation. PLoS One 8(8):e69898.